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3-Hydroxybutyrate dehydrogenase (3-HBDH) is a mitochondrial enzyme crucial for ketone body metabolism. It serves as the final enzyme for ketone synthesis in the liver and the initial enzyme for ketone breakdown in extracellular tissues. Its absence can lead to inhibited fatty acid oxidation in the liver during fasting, resulting in lipid accumulation and the development of fatty liver.
Mitochondrial enzyme
Key enzyme in ketone body metabolism
Last enzyme for ketone synthesis in the liver
First enzyme for ketone breakdown in extracellular tissues
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Tribioscience Glutamate dehydrogenase (GDH) activity Quantification Colorimetric Assay is based on a dehydrogenase coupled reaction convert chromophore to a colored formazan, which can be measured at OD 460 nm. The generated signal is proportional to the content of NADPH. This assay specifically detects GDH activity from the cell lysate. The kit provides the easiest and most accurate approach to measure GDH activity from a variety of samples.
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• For quantitative determination of protein in cerebrospinal fluid and urine for both manual and automated systems • Standards and Controls are stable until the expiration date when stored at 2ºC–8ºC • The kit consists of four protein standards:Level 2 (25 mg/dL), Level 3 (50 mg/dL), Level 4 (100 mg/dL), and Level 5 (200 mg/dL)
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A flavonoid glucoside with diverse biological activities scavenges DPPH radicals in a cell-free assay (IC50 139.62 Ug/ml) inhibits the proliferation of Raji lymphoblasts but not isolated human PBMCs at 20 UM induces apoptosis decreases levels of COX-2 VEGF PI3K and phosphorylated Akt and increases levels of PTEN in SMMC-7721 cells at 1.63 UM reduces tumor weight and volume and increases survival in a Raji mouse xenograft model at 30 mg/kg per day decreases plasma levels of triglycerides total cholesterol LDL ALT AST TNF-a and IL-6 and reduces liver levels of TNF-a and IL-6 in rats fed a high-fat diet at 200 mg/kg per day
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The R-PLEX Human IL1RL1/ST2 Assay Kit from Meso Scale Discovery measures IL1RL1/ST2 in human serum plasma and cell culture supernatants using electrochemiluminescence (ECL) detection It offers high sensitivity a 5-log dynamic range and low sample volume requirements The kit includes a 96-well plate with capture antibodies ECL-labeled detection antibodies and necessary calibrators and controls The assay takes about 3 hours and is compatible with MSD platforms providing a sensitive and reproducible method for quantifying IL1RL1/ST2 levels
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BNP and NT-proBNP are separated from precursor molecule proBNP via proteolytic processing The BNP and NT-proBNP level in blood are proportional to the severity of cardiac dysfunction They can be used for diagnosis of congestive heart failure (CHF)
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Fenpyrazamine Standard is a high-purity analytical reference material designed for pesticide residue analysis Supplied as a white crystalline powder it offers 98 0% purity as determined by both HPLC and qNMR methods This compound is practically insoluble in water but readily soluble in organic solvents such as acetone and ethanol It is intended for research use only and is especially suitable for environmental and food safety laboratories requiring accurate quantification of fenpyrazamine residues The product must be stored in a tightly sealed container at 2 10C protected from light and moisture Classified as environmentally hazardous UN3077 it should be handled in accordance with all relevant safety and transport regulations
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